SAS Institute Alert Note SN-008625

From: SAS Technical Support (
Date: Thu Nov 21 2002 - 09:03:23 EST

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    SN-008625 ***Alert Note***

    The Likelihood Ratio Test Statistic for the Marker-Trait Association in
    PROC HAPLOTYPE is incorrect

    Product: SAS/Genetics
    Component: HAPLOTYPE procedure
    Priority: ALERT

      The Likelihoood Ratio Test (LRT) statistic and its associated p-value
      for the Marker-Trait Association in PROC HAPLOTYPE are incorrect. The
      correct Likelihood Ratio statistic can be obtained by multiplying the
      value of the Chi-Square statistic that is reported by 2. The p-value
      for the LRT reported in the the column "Pr>Chisq" is also incorrect.
      To obtain the correct p-value, use the PROBCHI function in the DATA
      STEP. The correct p-value can be calculated as:

         p_value = 1 - probchi(chisq,df);

      where chisq is the corrected Chi-Square statistic, and df is equal to
      the sum of the degrees of freedom of each TRAIT variable, minus the
      degrees of freedom reported in the row "COMBINED".

      likelihood ratio test statistic marker trait association proc haplotype
      sas genetics incorr wrong
      the likelihood ratio test statistic for the marker-trait association in
      proc haplotype is incorrect
      008625 8625

    SAS Note Revised On: Fri, 11 Oct 2002

    System Version Reported Version Fixed

    AIX 64 bit 8.2 TS2M0 9
    AIX/6000 8.2 TS2M0 9
    Compaq Tru64 UNIX 8.2 TS2M0 9
    HP-UX Operating Systems 8.2 TS2M0 9
    HP-UX 64 bit 8.2 TS2M0 9
    Intel ABI 8.2 TS2M0 9
    Solaris 8.2 TS2M0 9
    Solaris 64 bit 8.2 TS2M0 9
    Windows NT 8.2 TS2M0 9

    No Fixes Available

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